Ascitic fluid analysis in hepatocellular carcinoma

Hepatocellular Carcinoma in Sheep

Hepatocellular carcinoma in a sheep

At necropsy of a five-year-old sheep, a pear shaped, lobular yellow-brownish mass measuring about 12 ×15 × 20 cm was found to involve the right hepatic lobe. Microscopic examination revealed two trabecularand solid patterns of neoplastic hepatocytes. In solid pattern, there were numerous tumoral giant cells thatcontain one or more large hyperchromatic bizarre-shaped nuclei scattered among clust...

Ascitic Fluid Analysis for the Differentiation

The authors tried to differentiate malignancy-related from nonmalignant ascites with a sequence of sensitive followed by specific ascitic-fluid parameters. There were four results of this study. First, of nine parameters investigated in a first series of 48 patients, 28 with nonmalignant and 20 with malignancy-related ascites, ascitic-fluid cholesterol and fibronectin yielded the best negative ...

Apoptotic neutrophils in ascitic fluid.

A 60-year-old man with known hepatitis C, cirrhosis, and mild hepatosplenomegaly was admitted for ascites. He had pancytopenia with leukocyte count 2.6 3 10/L, mild neutropenia 1.6 3 10/L, macrocytic anemia, and mild thrombocytopenia. Elevated international normalized ratio, low albumin, high bilirubin, and elevated liver enzymes were noted. Therapeutic paracentesis was performed, and ascitic f...

Molecular cloning of a defective hepatitis C virus genome from the ascitic fluid of a patient with hepatocellular carcinoma.

A defective hepatitis C virus (HCV) genome in the ascitic fluid of a patient with hepatocellular carcinoma was cloned and sequenced up to the 3' poly(U) stretch. When compared with the published Taiwanese HCV sequence, this defective genome contained deletions of single nucleotides at eight sites, double nucleotides at two sites, triple nucleotides at four sites, quadruple nucleotides at one si...